Effects of Ethanolic Seed Extract of Dacryodes Edulis on the of Paraquat Induced on Testicular Toxicity in Male Adult Wistar Rats

Dacryodes edulis, a multipurpose plant contains high concentrations of antioxidants, anti-inflammatory agents that protect against tissue damage. The study was aimed at determining the ethanolic seed extract dacryodes edulis on paraquat induced testicular toxicity in male adult wister rat. Fifty-four albino rat weighing between 150-180g were used for study. LD 50 determined both dacryodesedulis and paraquat. rats this experiment distributed into eight groups. Group A (control group) while B C D E F G H treated group. (group 0.1ml only for4 weeks, group 2 + 500mg/kg weeks discontinued, +1000mg/kg 4 weeks’ received 1000mg/kg weeks. At end animals anesthetized samples collected assessment. result from shows produces destructive effects testes evaluations, There significant increase LH, FSH testosterone level, F. also decrease body weight relative organ throughout period administration. Histopathological finding reveals distortion tissues with mild B. showed sign recovery reversal effect In conclusion possess ability to improve sperm morphology toxicity.